A welcome Letter from the Local Organising Committee
Dear Friends and Colleagues,
On behalf of the organising committee, I would like to extend our warmest welcome to the 10th International Symposium of the Society for Research on the Cerebellum and Ataxias (SRCA 2019) to be held in Sheffield, UK (May 16-17, 2019).
The annual symposia of the SRCA have become one of the definitive meetings on the Cerebellum, addressing all aspects of cerebellar research, from basic science to the ataxias. The 2019 meeting strives to maintain this tradition of excellence.
We have selected as the venue The Cutler’s Hall, a magnificent Grade II listed building in the heart of Sheffield City Centre, linked to the history of the steel industry for which Sheffield is famous. The Cutler’s Company that build the Hall was established in 1624 and for almost 400 years has sought to maintain the standards and quality of Sheffield manufactured cutlery and steel products and to promote the name of Sheffield all over the world.
The local organising committee and the SRCA Symposium Committee have worked hard to design a program of lectures by eminent international speakers reflecting the aspiration of the SRCA: to promote education by supporting basic and clinical research into the neuroscience of the cerebellum.
We look forward to welcoming you to Sheffield.
Professor Marios Hadjivassiliou
On behalf of the local organising committee
The venue : The Cutlers’ Hall.
The Cutlers' Hall is Sheffield's most prestigious venue, set in the heart of the city centre.
With Cutlers' Hall based in the heart of the city it becomes the ideal venue of the SRCA symposium in Sheffield with the mainline Sheffield train station just a 5 minutes taxi ride or direct link via supertram to outside the venue.The hall has flexible rooms and layout which means they can host small meetings in the beautiful Hallamshire Suite for eight guests or large conference event so for up to 500 delegates – all within this diverse central Sheffield venue.
Cutlers' Hall is a magnificent Grade II listed venue in the heart of Sheffield City Centre with excellent transport links and an abundance of accommodation within a short walking distance.
Sheffield S1 1HG
Travelling to Sheffield by Air:
With 4 international airports within less than an hour's drive, Sheffield is easy to reach from overseas destinations.
Manchester Airport, one of the UK's busiest, has a regular direct rail service to Sheffield. Robin Hood Doncaster Sheffield Airport is served by a number of European destinations with charter flight routes. Leeds Bradford Airport is also well served by European and long haul destinations. Sheffield can be reached by using a taxi service or bus to Leeds and then train to Sheffield.
Nottingham East Midlands receives routes from European and long haul destinations. Sheffield can be reached by road using a taxi service, or take the airport shuttle to East Midlands Parkway and take the train (operated by East Midlands Trains) to the centre of Sheffield.
To ensure your easy onward journey from your airport of choice, why not book your airport transfer in advance with one of the private hire taxi companies in Sheffield. You can book City Taxis online or call them direct on 0114 239 3939 or travel using UBER
Travelling to Sheffield by train:
If you are travelling from London, or on routes operated by East Midlands Trains, you might find our 'special event tickets' a value for money travel option.
The mainline station in Sheffield offers an impressive entry to the City, with fast direct links from London St Pancras International departing every 30 minutes from early morning to late at night. Coming in from Europe? The Eurostar link from Paris arrives at London St Pancras International - you can be in Sheffield in just 5 hours after leaving Paris.
The journey from London is now only 2hrs and 1mins , the service is operated by East Midlands Trains with both First and Standard Class seating available. There are also hourly fast trains from Manchester City Centre and direct services from Manchester International airport.
Regional Train Services:
Sheffield is so easy to reach by train, whether you're travelling from North, South, East or West. Take a look at the special offers from TransPennine Express or at the services provided by Northern Rail as great starting points to planning your visit.
Reduced travel fees
Ferdinando Rossi Memorial Lecture
08:30- 09:30 Cerebellum: Motor control and beyond Chris Miall (Birmingham)
Cerebellar circuits and Functional anatomy
09:30-10.00 Cellular imaging of cerebellum during behavior Dimitar Kostadinov (UCL)
10.00-10.30 Functional imaging of the cerebellar nuclei Dagmar Timman (Essen)
10.30-11.00 coffee break and poster viewing
11.00-11.30 Functional cerebellar connectivity: what does Xavier Guell (Boston)
fMRI tell us
11.30-12.00 From cerebellar circuits and functional anatomy
to disease: Clinical imaging of the ataxias N Hoggard (Sheffield)
12.00-12.30 New developments in genetic testing: A Nemeth (Oxford)
genome sequencing and beyond
12.30-1300 SPG7: the new kid on the block C Hewamadduma (Sheffield)
13.00-14.00 Lunch and poster viewing
Cerebello-cerebral connectivity and function
14.00-14.30 Anatomic principles Thomas Ruigrok (Erasmus)
14.30-15.00 Sensorimotor interactions C Lena (Paris)
15.00-15.30 Higher level processing N Ramnani (London)
15.30-16.00 Myolconic ataxia: the myoclonus is cortical P Sarrigiannis (Sheffield)
but the pathology is in the cerebellum.
16.00-16.30 Coffee break and poster viewing
Cerebellum and autism
16.30-17.00 The role of the cerebellum in cognition C Marvel (Baltimore)
17.00-17.30 Autism and classical eyeblink conditioning J Welsh (Seattle)
17.30-18.00 The cerebellum and autism: from structure to function S Doesburg (Canada)
Mechanisms of cerebellar damage
08.30-09.00 Degeneration: Cerebellar variant of multiple system atrophy C Raccagni (Innsbruck)
09.00-09.30 Mitochondrial Dysfunction: The cerebellum in Y Ng (Newcastle)
09.30-10.00 Defective DNA repair: What can we learn from Malcolm Taylor (Birmingham)
10.00-10.30 Toxicity: Alcohol and the cerebellum P Shanmugarajah (Sheffield)
10.30-11.00 coffee brake and poster viewing
Pathophysiology of autoimmune ataxias
11.00-11.30 Paraneoplastic cerebellar degeneration J Honorat (Lyon)
11.30-12.00 Anti-GAD ataxia H Mitoma (Japan)
12.00-12.30 Gluten ataxia M Hadjivassiliou (Sheffield)
12.30-13.00 Role of transglutaminases in the ataxias D Aeschlimann (Cardiff)
13.00-14.30 lunch and poster viewing
14.30-15.00 Experimental results in cerebellar reserve- A Buffo (Turin)
from autophagy to motor training
15.00-15.30 Morphological synaptic changes and L Petrosini (Rome)
15.30-16.00 Ocular motor cerebellar reserve: from primate A. Shaikh (Cleveland)
physiology to clinical translation
16.00-16.30 Treatment studies in degenerative ataxias: SH Subramony (Florida)
What can we learn?
16.30-17.00 Closing comments and discussion, Masao Ito award for best poster
Registration and Hotels
Hotel accommodation can be booked through the services of our partner.
Making bookings: Reservations can be made using the web address below until 28 days prior to the event start date. On this date some hotels will choose to leave unsold rooms on the system, or they may remove them. The site will close fully 14 days prior to the event start date. After this date contact details for hotel will be given for last minute inquiries. As more bookings are made, this encourages hotels to leave their rooms on the system for as long as possible, so please encourage delegates to book early.
Book your hotel room here:
Hotel room reservation
Known the world over as “The Steel City”, Sheffield was famed for its industry in the heyday of the 1900’s and remains a city of innovation to this day. However the smoking chimney stacks are no more and instead you’ll find a green, modern cityscape set against the stunning backdrop of the Peak District National Park.
We have a friendly, independent and alternative spirit that you won’t find in other cities, alongside a thriving cultural scene boasting award-winning theatre, beer, music, festivals, street art and so much more.
Just a bit of History:
Escafeld, as the historic town of Sheffield was called at the time of Domesday Book (1086), was an Anglo-Saxon village. It became the site of a castle and a parish church built by the Norman lord William de Lovetot early in the 12th century. From medieval times the local iron ore was smelted with charcoal obtained from the nearby abundant woodlands, and smiths and cutlers used the excellent local sandstone for grindstones. During the 15th century the streams that converge on Sheffield began to be used for power for grinding and forging operations. A cutlery industry thus grew, and Sheffield emerged in the 17th century as the main provincial cutlery town and a powerful rival to London. By 1700 London, too, had been defeated, and thereafter Sheffield enjoyed a virtual monopoly of the English cutlery trade.
Sheffield was the site of several metallurgical innovations that greatly spurred its growth. In the early 1740s Benjamin Huntsman developed the crucible process of steelmaking, thereby obtaining a reliable tool steel that by 1830 had earned Sheffield recognition as the world centre of high-grade steel manufacture. About 1742 the Sheffield cutler Thomas Boulsover discovered the process of plating copper with silver by fusion, and the city became the chief production centre for articles made of Sheffield plate. Henry Bessemer’s new method (1856) of making inexpensive steel in large quantities was first tested and used in a factory at Sheffield, whose heavy steel industries grew greatly as a consequence. The process for making stainless steel also originated at Sheffield, about 1912. In 1911 census returns showed that Sheffield had surpassed Leeds as the most populous city in Yorkshire.
Although its industrial base underwent some shrinkage in the late 20th century, Sheffield is still a major British producer of raw steel, cutlery, and machinery. Food processing is also important. Sheffield is sited on a hill-and-valley system of great beauty, and both the moors of the Pennines and the wooded dales of Derbyshire sweep up to the very edge of the city’s residential areas. Outside the town of Sheffield, the metropolitan borough includes suburban areas and open countryside.
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