The 13th International Symposium of The Society for Research on the Cerebellum and Ataxias


Membrane molecules, Models & Modulating Neurons...
Approching Bedside to Bench and Back


May 10 - 12, 2024 in Mumbai, India

INVITATION

Save the Date: May 10-12, 2024

The Board of the SRCA and its local partners invites you and your colleagues to attend the upcoming 13th International Symposium. This meeting is organised in loving memory of
Prof. Bing-Wen Soong.


Symposium Programme

Day 1 - Plenary session - Friday May 10, 8am - 8pm

Session 1

Chair: Aasef Shaikh

08:30

Lecture 1: Eye movements and the cerebellum: a tour through a century of progress.

David Zee - Johns Hopkins University, USA

Session 2: Computational Neuroscience in Cerebellum

Chair: Cécile Gallea

09:30

Lecture 2: Internal models of self-motion: neural computations by the vestibulo-cerebellum

Kathy Cullen - Johns Hopkins University, USA

10:00

Lecture 3: Models of vestibular system in cerebellar disease

Jeongyoon Choi - Seoul National University, S. Korea

10:30

Lecture 4: Dynamics of ocular motor control: contemporary concepts of neural integrators to adaptation

Jorge Otero-Millan - University of California Berkeley, USA

11:00

Panel Discussion

11:15

Refreshments

Session 3: Therapeutics, diagnostics and more

Chair: Jorge Kattah

11:30

Lecture 5: Pharmacotherapy of cerebellar disorders

Michael Strupp - Ludwig Maximilian University, Germany

12:00

Lecture 6: View of immune opsoclonus from lenses of membranes,mathematical models, and clinical medicine

Aasef Shaikh - University Hospitals and Case Western Reserve University, USA

12:30

Lecture 7: Cerebellar structural changes in neurological diseases: New insights from big data neuroimaging

Ian Harding - QIMR Berghofer Medical Research Institute, Australia

13:00

Panel Discussion

13:15

Lunch

Session 4: Animal Models and Transmitter Imaging

Chair: Aparna Wagle-Shukla

14:15

Lecture 8: Cerebellar features of essential tremor – The clinical data

Elan Louis - UT Southwestern Medical Center, USA

14:45

Lecture 9: Three pathophysiologies of action tremor: implications in essential tremor therapeutic development

Sheng-Han Kuo - Columbia University, USA

15:15

Lecture 10: Cerebellar mutant mice as models for cerebellar syndromes

Jan Cedenlin - Charles University in Prague, Czech Republic

15:45

Lecture 11: Ataxic mouse model of ataxia-telangiectasia

Paul Mathews - The Lundquist Institute and David Geffen School of Medicineat UCLA, USA

16:15

Panel Discussion

16:30

Coffee Break

Session 5: Regeneration, Neurodevelopment

Chair: Nori Koibuchi

16:45

Lecture 12: The effect of thyroid hormone on functional development of the cerebellum

Ayane Kate Ninomiya - Gunma University, Japan

17:15

Lecture 13: Purkinje cell activity in cerebellar development

Catarina Osorio - Erasmus University Medical Center, The Netherlands

17:45

Panel Discussion

18:00

Lecture 14: The clinical spectrum of ocular laterodeviation in medullary and cerebello-medullary lesions

Jorge Kattah - University of Illinois at Chicago, USA

18:30

Lecture 15:
Sponsored Talk: Head-unrestrained gaze shifts are controlled by a central feedback loop through the cerebellum. From a model to an experimental demonstration

Pierre Daye - P3 Lab, Belgium

19:00

Lecture 16: The foundation of cerebellar circuitry: Early development and connectivity formation of cerebellar nuclei

Hassan Marzban - University of Manitoba, Canada

20:00

Dinner & Welcome
Day 2 - Plenary session - Saturday May 11, 8am - 7pm

Session 1

Chair: Aasef Shaikh

08:00

Lecture 1: Spinocerebellar ataxia and beyond: new models and mechanisms

Esther Becker - University of Oxford, UK

Session 2:

Chair: Alexander Tarnutzer

09:00

Lecture 2: Cognition in cerebellar ataxia

Louisa Selvadurai - Monash University, Australia

09:30

Lecture 3: Gluten Ataxia

Marios Hadjivassiliou - University of Sheffield, UK

10:00

Lecture 4: Monoamines and mitochondria-implications for neuroprotection

Vidita Vaidya - Tata Institute of Fundamental Research and Indian Institutes of Technology, India

10:30

Lecture 5: Discovering the biology of neuropsychiatric illness in India

Biju Viswanath - National Institute of Mental Health & Neurosciences, India

11:00

Panel Discussion

11:15

Refreshments

Session 3: Cerebellum and Tremor

Chair: Alessandro Serra

11:30

Lecture 6: Cerebellar pathology of essential tremor

Phyllis Faust - Columbia University, USA

12:00

Lecture 7: Frequency coding of the cerebellum in tremor generation

Ming-Kai Pan - National Taiwan University College of Medicine, Taiwan

12:30

Lecture 8: Pharmacotherapy of eye and hand oscillations in cerebellar disorders

Alexander Tarnutzer - Kantonsspital Baden AG, Baden, Switzerland

13:00

Lecture 9: Functional brain network in essential tremor and dystonic tremor

Aparna Wagle-Shukla - University of Florida, USA

13:30

Panel Discussion

13:45

Lunch

Session 4: Cerebellum Connectivity with Basal Ganglia and Beyond

Chair:Traian Popa

14:45

Lecture 10: New concepts on the physiological interdependence of cerebellar, striatal and cortical circuits during learning

Cécile Gallea - National Institute of Neurological Disorders and Stroke, France

15:15

Lecture 11: New theories for ocular-palatal tremor; inferior olive, cerebellum, and beyond

Jorge Kattah - University of Illinois at Chicago, USA

15:45

Lecture 12: Integrative Network Models involving pallidum and cerebellum in dystoniaL

Alexey Sedov - Semenov Institute of Chemical Physics Russian Academy of Sciences, Russia

16:15

Panel Discussion

16:30

Refreshments

Session 5: Cerebellar genetics

Chair: Roopa Rajan

16:45

Lecture 13: Repeat expansion gene discovery and novel testing methodologies in cerebellar ataxia

Paul Lockhart - Murdoch Children's Research Institute, Australia

17:15

Lecture 14: Bioinformatics in cebellar ataxia gene discovery

Melanie Bahlo - Walter and Eliza Hall Institute of Medical Research, Australia

17:45

Lecture 15: Head-unrestrained gaze shifts are controlled by a central feedback loop through the cerebellum. From a model to an experimental demonstration

David Szmulewicz - Balance Disorders and Ataxia Service, Royal Victorian Eye and Ear Hospital, Australia

18:15

Lecture 16: CACNA1A mutations in cerebellar disorders

Heather Snell - Yale University School of Medicine, USA

18:45

CACNA1A Foundation

An outreach story

19:00

Panel Discussion

20:00

Gala Dinner with Cultural Programme
Day 3 - Parallel session 1 - Sunday May 12, 8am - 5pm

Session 1: Clinical Didactic

Chair: Sangeeta Ravat

08:00

Lecture 1: Botulinum toxin for cerebellar and non cerebellar tremor

Shivam Mittal - Cleveland Clinic Abu Dhabi, United Arab Emirates

08:30

Lecture 2: Eye movements in multiple sclerosis

Alessandro Serra - University Hospitals and Case Western Reserve University, USA

09:00

Lecture 3: Tele-neuro-otology

Sudhir Kothari - Pune Hospital, India

09:30

Lecture 4: Eye movements in emergency and critical care medicine

U. Meenakshisundaram - Arumai Neuro-Center, India

10:00

Panel Discussion

10:15

Refreshments

Session 2: Clinical Didactic

Chair: U. Meenakshisundaram

10:30

Lecture 5: Benign paroxysmal positional vertigo and positional nystagmus

Anirban Biswas -Vertigo & Deafness Clinic, India

11:00

Lecture 6: Technological advances in diagnosis and treatment of dizziness and balance disorders

Anita Bhandari - Vertigo and Ear Clinic, NeuroEquilibrium, Mahatma Gandhi Medical College and Hospitals, India

11:30

Lecture 7: Autonomic-vestibular interaction

Sun-Uk Lee - Korea University Medical Center, S. Korea

12:00

Lecture 8: Kaleidoscope of ataxia in the clinic

Pankaj Agarwal - Gleneagles Hospital and KEM Hospital Mumbai, India

12:30

Lecture 9: Spinocerebellar Ataxias type 12

Achal Srivastava - All India Institute of Medical Sciences, India

13:00

Lecture 10: Genetics of cerebellar disorders

Pettarusp Wadia -Jaslok Hospital Mumbai, India

13:30

Lunch

Session 3: Clinical Didactic

Chair: Sudhir Kothari

14:00

Lecture 11: A few interesting cases of ataxia

Screenivas Um - MGM Healthcare Multi-Specialty Hospital, India

14:30

Lecture 12: Tremor in spinocerebellar ataxia

Sanjay Pandey - Amrita Hospital, India

15:00

Lecture 13: Approach to cerebellar tremor

Roopa Rajan - All India Institute of Medical Sciences, India

15:30

Lecture 14: Biomarkers in Cerebellar Ataxia

Abdullah Alquatani - National Institute of Health, USA

16:00

Lecture 15: Downbeat nystagmus

Parthvi Ravat - KEM Hospital, India

16:30

Conclude:
Day 3 - Parallel session 2 - Sunday May 12

08:00

INVITED LECTURE : Low intensity repetitive magnetic stimulation (LI-rTMS) improves pathological cerebellar development in a mouse model of neurodevelopmental disorders

Rachel Sherrard - Sorbonne Université, France

08:30

Short Talk 1 : Deciphering the role of type 1 metabotropic glutamate signalling in the progression of spinocerebellar ataxia type 1

Mohamed Fasil Ibrahim - University of Oxford, UK

08:45

Short Talk 2 : The primary cilia deficiency in the mouse model of spinocerebellar ataxia type 1

Jan Tuma - Charles University, Faculty of Medicine in Pilsen, Czech Republic

09:00

Short Talk 3:The cerebellum's role in self-motion perception

Aratrik Guha - Case Western Reserve University, USA

09:15

Panel Discussion

09:30

Short Talk 4: Effects of strabismus and nystagmus on saccades and visual search

Ibrahim Quagraine - Case Western Reserve University, USA

09:45

Short Talk 5: Proprioception and cerebellar connectivity in dystonia: impact on pallidal physiology

Prajakta Joshi - Case Western Reserve University, USA

10:00

Short Talk 6: Neural integrator network model for task-specific head tremor

Paul Wang - Case Western Reserve University School of Medicine and University Hospitals Cleveland Medical Center, USA

10:15

Panel Discussion

10:30

Refreshments

10:45

Short Talk 7: Cerebellum lesions radiosurgery with CyberKnife system

Kaile Li - Varian Medical System, USA

11:00

Short Talk 8: Discovering the biology of major psychiatric illness usinginduced pluripotent stem cells

Mythri SV - National Institute of Mental Health and Neurosciences, India

11:15

Short Talk 9: Deciphering cellular mechanisms of bipolar disorder and lithium response

Pradip Paul - National Institute of Mental Health and Neurosciences, India

11:30

Short Talk 10: Ataxia in cerebrovascular disease

Neetu Ramrakhiani - Fortis Escorts Hospital Jaipur, India

11:45

Panel Discussion

12:00

Short Talk 11: Pontocerebellar hypoplasia with proximodistal motor axonal neuropathy due to a novel VRK1 mutation - first case report from India

Koustubh Bavdhankar - Seth GSMC and KEM Hospital Mumbai, India

12:15

Short Talk 12: GAA repeat expansion in the first intron of FGF14 causing spinocerebellar ataxia-27B in the Indian population

Pannaga Prasad G - National Institute of Mental Health and Neurosciences, India

12:30

Short Talk 13: Diagnostic delay in pediatric vestibular disorders

Payal Kumbhat - RUHS Medical College, India

12:45

Short Talk 14: All that glitters is not gold

Koustubh Bavdhankar - Seth GSMC and KEM Hospital Mumbai, India

13:00

Panel Discussion

13:15

Conclusion of Short Talks: